Year of birth: 1981
Alternative civilian service: 2001-2002
Education and qualification:
| 2002 - 2007 | study of biology at the University of Karlsruhe |
| 2006 | three month-project in the lab of PD Dr. Eva Zyprian at the "Institut für Rebenzüchtung Geilweilerhof" in Siebeldingen, Germany; work on a BAC-library of the grape cultivar "Regent" |
| 2007 | diploma thesis “Etablierung und Anwenung molekulargenetischerMethoden zur Charakterisierung von RecQ-Helikasen und ihren Interaktionspartnern in Arabidopsis thaliana“ (“Establishment and application of methods of molecular genetics to characterize RecQ helicases and their interaction partners in Arabidopsis thaliana”) |
| 2011 | PhD thesis "Rolle der DNA-Helikasen FANCM, SRS2 und RTEL1 in der somatischen und meiotischen homologen Rekombination von Arabidopsis thaliana" at the Botanical Institute II |
| since 2011 | Postdoc at the Botanical Institute II |
Employment:
| since 2007 | Botanical Institute II, Plant Molecular Biology and Biochemistry, Karlsruhe Institute of Technology |
Duties:
Supervision of diploma students and practicals
Supervision of lab technicians and trainees
Areas of interest:
mechanisms of genes and proteins involved in homologous recombination
telomeres
gene silencing and RNAi
introns early/introns late
evolution
Current projects
characterization of RecQ helicase mutants and their interaction partners in A. thaliana
Memberships
German Society for Biochemistry and Molecular Biology (Gesellschaft für Biochemie und Molekularbiologie, GBM)
Federation of European Biochemical Societies (FEBS)
International Union of Biochemistry and Molecular Biology (IUBMB)
Publications:
Knoll A., Higgins J.D., Seeliger K., Reha S.J., Dangel N.J., Bauknecht M., Schröpfer S., Franklin F.C.H. and Puchta H. (2012). The Fanconi Anemia Ortholog AtFANCM Ensures Ordered Homologous Recombination in Both Somatic and Meiotic Cells in Arabidopsis thaliana. Plant Cell 24, 1448-1464
Knoll A. and Puchta H. (2011) The role of DNA helicases and their interaction partners in genome stability and meiotic recombination in plants. Journal of Experimental Botany. J. Ex. Bot, 62: No 5, 1565–1579.
Puchta H, Kobbe D, Wanieck K, Knoll A, Suer S, Focke M and Hartung F. (2009) Role of Human Disease Genes for the Maintenance of Genome Stability in Plants. In: Q.Y. Shu (ed.), Induced Plant Mutations in the Genomics Era. Food and Agriculture Organization of the United Nations, Rome, 2009, 129-132
Kortekamp A, Welter L, Vogt S, Knoll A, Schwander F, Töpfer R and Zyprian E. (2008): Identification, isolation and characterization of a CC-NBS-LRR candidate disease resistance gene family in grapevine. Molecular Breeding 22(3):421-432.
Hartung F., Suer S., Knoll A., Wurz-Wildersinn R. and Puchta H. (2008) Topoisomerase 3A and RMI1 suppress somatic crossovers and are essential for resolution of meiotic recombination intermediates in Arabidopsis thaliana. PLoS Genet 4(12): e1000285.
